128-Channel Recording, 32-Channel Stimulation, Digitally Interfaced Optogenetic Neuromodulation System-on-Chip

Sang Min Song; Min Jae Kim; Joon Gyu Kim; Hyun Tae Park; Young Hoon Park; Kyung Sik Eom; Sung Yun Park

doi:10.23075/jicas.2022.8.2.001

Sang Min Song Pusan National University
Min Jae Kim Pusan National University
Joon Gyu Kim Pusan National University
Hyun Tae Park Pusan National University
Young Hoon Park Pusan National University
Kyung Sik Eom Pusan National University
Sung Yun Park Pusan National University

DOI: https://doi.org/10.23075/jicas.2022.8.2.001

Keywords: Application Specific Integrated Circuit(ASIC), Multichannel neural recording and stimulation, Neuromodulation, Optogenetics

Abstract

This paper presents a digitally interfaced a 128-channel recording, 32-channel stimulation optogenetic neuromodulation system on chip (SoC) that has been developed for long-term optogenetics neuroscience research. The low-power 128-channel neural recording frontend offers low-noise multichannel recording, on-chip 16-bit data digitization, and electrode impedance measurement. The 32-channel optogenetic stimulator provides high-resolution, accurate optical stimulation. The chip communicates through two control signal shared SPI interfaces for simultaneous recording and stimulation with independent on-the-fly control command and data transfer, resulting in only 6 external wires. The developed system constitutes a fully digital, bidirectional 128/32-channel neuromodulation SoC to the animal-under-test.

Author Biographies

Sang Min Song, Pusan National University

Sang Min Song received his B.S. in Electronic Engineering from Pusan National University, Busan, Korea in 2021, where he is currently working toward the M.S. degree in electrical and electronics engineering. His current research interests are in low-power, low-noise, high power conversion efficiency DC-DC converters and photodiode with MPPT controller.

Min Jae Kim, Pusan National University

Min Jae Kim received his B.S. in Electronic Engineering from Pusan National University, Busan, Korea in 2021. His current research interests are in low-power, low-noise OTA for neural signal recording.

Joon Gyu Kim, Pusan National University

Joon Gyu Kim received his B.S. in Electronic Engineering from Pusan National University, Busan, Korea in 2021, where he is currently working toward the M.S. degree in electrical and electronics engineering. His current research interests are Two-Step SAR ADC Architecture using Time-Domain Comparator for low power and high resolution in CMOS designs.

Hyun Tae Park, Pusan National University

Hyun Tae Park received his B.S. in Electronic Engineering from Pusan National University, Busan, Korea in 2021, where he is currently working toward the M.S. degree in electrical and electronics engineering. His current research interests include time-domain VCO based Zoom ADC and incremental delta-sigma ADCs for low power and high resolution in CMOS designs.

Young Hoon Park, Pusan National University

Young Hoon Park received B.S. degree in Electronics Engineering from Pukyong National University (PKNU), Busan, S. Korea, in 2020. His current research interests include the development of neural prostheses, especially retinal prostheses, and the development of safe and effective neural interfaces.

Kyung Sik Eom, Pusan National University

Kyung Sik Eom received B.S. degree in Electrical and Electronics Engineering from Korea Advanced Research Institute (KAIST), Daejeon, S. Korea, in 2010, the M.S. and Ph.D. degree in Electrical and Computer Engineering from Seoul National University, Seoul, S. Korea, in 2012 and 2016, respectively. From 2016 to 2019, he was involved in developing a novel photonic retinal prosthesis using plasmonic nanoparticles as a post-doctoral research associate in the Department of Engineering at Brown University, RI, USA. In 2019, he joined the Department of Electronics Engineering at Pusan National University, Pusan, S. Korea, as an assistant professor. His current research interests include developing neural prosthesis especially the retinal prosthesis, developing safe and effective neural interface, and optical imaging tools for ophthalmology.

Sung Yun Park, Pusan National University

Sung-Yun Park received the B.S. degree in electrical engineering from Pusan National University, Busan, Korea, in 2005, the M.S. degree in electrical engineering from the Korean Advanced Institute of Science and Technology (KAIST), Daejeon, Korea, in 2008, and the M.Eng. degree in electrical and computer engineering and the Ph.D. degree in electrical engineering from the University of Michigan in 2011 and 2016, respectively. He was involved in photonics device research with the Korean Advanced Institute of Science and Technology. From 2008 to 2010, he was a Member of the Technical Staff with Fairchild Semiconductor, Bucheon, Korea, for high voltage mixed signal circuit design. He continued his study in integrated circuits with Cornell University, Ithaca, NY, USA. From 2016 to 2018, he was a Research Fellow with the University of Michigan, where he has been an Assistant Research Scientist since 2018. In 2019, he joined the Department of Electronics Engineering, Pusan National University, where he is an Assistant Professor. His current research interests are low power, low noise mixed-signal integrated circuits and power management circuits for biomedical and sensor systems.

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