Microscale Wireless Electrical Stimulators for Electroceutical Applications: a Review
Abstract
Electroceutical has been used as an attractive approach to disease treatment, using electrical stimulation to modulate the metabolic function and restore body homeostasis. As the first generation of electroceuticals, cardiac pacemakers and implantable defibrillators have saved countless lives over several decades. Due to the remarkable technological progress of implantable medical systems over the past few years, it has reached the point of transforming the existing system into a micro-scale system using semiconductor microelectronics. Herein, research trends regarding various disease applications of electroceuticals are reviewed. In particular, the components, specifications, and circuit structures of the stimulation sub-systems in electroceuticals are thoroughly reviewed.